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Antibody Product Overview
| ELK.No | ES13260 |
| Product name | S23A1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9963 |
| Human Swiss-Prot | Q9UHI7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | S23A1 |
| Fields | >>Vitamin digestion and absorption |
| Gene name | SLC23A1 SVCT1 YSPL3 |
| Protein name | S23A1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20522 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z2J0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 50621 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9WTW7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human S23A1 AA range: 237-287 |
| Specificity | This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 66kD |
| Observed band (KD) | |
| Background | The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008], |
| Function | alternative products:Experimental confirmation may be lacking for some isoforms,function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13260-50
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