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Antibody Product Overview
| ELK.No | ES13266 |
| Product name | S20A2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6575 |
| Human Swiss-Prot | Q08357 |
| Source | Rabbit |
| Isotype | IgG |
| Target | S20A2 |
| Fields | |
| Gene name | SLC20A2 GLVR2 PIT2 |
| Protein name | S20A2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20516 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80UP8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29502 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63488 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human S20A2 AA range: 370-420 |
| Specificity | This antibody detects endogenous levels of S20A2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 72kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012], |
| Function | function:Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.,induction:Increased by phosphate depletion in osteosarcoma cell lines.,similarity:Belongs to the inorganic phosphate transporter |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13266-50
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