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Antibody Product Overview
| ELK.No | ES13309 |
| Product name | RUN3B rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 154661 |
| Human Swiss-Prot | Q96NL0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RUN3B |
| Fields | |
| Gene name | RUNDC3B RPIB9 RPIP9 |
| Protein name | RUN3B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 242819 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6PDC0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 688590 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q3B7K9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human RUN3B AA range: 79-129 |
| Specificity | This antibody detects endogenous levels of RUN3B at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 52kD |
| Observed band (KD) | |
| Background | |
| Function | similarity:Belongs to the RUNDC3 family.,similarity:Contains 1 RUN domain.,subunit:Interacts with RAP2A.,tissue specificity:Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lines and in the primary tumor of breast cancer patients. Activation also correlates with metastatic lymph node invasion and can be detected in metastatic epithelial cells from the lymph nodes and in the bone marrow of patients., |
| Subcellular location | |
| Expression | Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lines and in the primary tumor of breast cancer patients. Activation also correlates with metastatic lymph node invasion and can be detected in metastatic epithelial cells from the lymph nodes and in the bone marrow of patients. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13309-50
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