Français
English
Antibody Product Overview
| ELK.No | ES13360 |
| Product name | RNF4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6047 |
| Human Swiss-Prot | P78317 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RNF4 |
| Fields | |
| Gene name | RNF4 SNURF RES4-26 |
| Protein name | RNF4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 19822 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QZS2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29274 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O88846 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human RNF4 AA range: 71-121 |
| Specificity | This antibody detects endogenous levels of RNF4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 21kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010], |
| Function | function:Enhances steroid receptor-mediated transcriptional activation as well as activating basal transcription.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with GSCL, Androgen receptor, TCF20, TBP and PATZ1.,tissue specificity:Widely expressed at low levels in many tissues; highly expressed in testis., |
| Subcellular location | Cytoplasm. Nucleus. Nucleus, PML body. Nucleus, nucleoplasm. |
| Expression | Widely expressed at low levels in many tissues; highly expressed in testis. |
Additional Images
No image
Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
No image
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
No image
No image
: AO-06-ES13360-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package