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Antibody Product Overview
| ELK.No | ES14556 |
| Product name | NAT8L rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 339983 |
| Human Swiss-Prot | Q8N9F0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NAT8L |
| Fields | >>Alanine, aspartate and glutamate metabolism;>>Metabolic pathways |
| Gene name | NAT8L CML3 |
| Protein name | NAT8L |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 269642 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3UGX3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 289727 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | D3ZVU9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human NAT8L AA range: 218-268 |
| Specificity | This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 33kD |
| Observed band (KD) | |
| Background | This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010], |
| Function | similarity:Belongs to the camello family.,similarity:Contains 1 N-acetyltransferase domain., |
| Subcellular location | Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. . |
| Expression | Expressed in brain. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14556-50
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