MYT1L rabbit pAb

MYT1L rabbit pAb

AO-06-ES14580-50

MYT1L rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES14580
Product nameMYT1L rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB;ELISA;IHC
Other name
Size50μL
Unit price ($)148
Human gene ID23040
Human Swiss-ProtQ9UL68
SourceRabbit
IsotypeIgG
TargetMYT1L
Fields
Gene nameMYT1L KIAA1106
Protein nameMYT1L
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtP97500
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID116668
Rat gene linkView Rat Gene
Rat Swiss-ProtP70475
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human MYT1L AA range: 595-645
SpecificityThis antibody detects endogenous levels of MYT1L at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)130kD
Observed band (KD)
BackgroundThis gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016],
Functionfunction:May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendrogalia in the CNS.,similarity:Contains 6 C2HC-type zinc fingers.,
Subcellular locationNucleus . Chromosome . Preferentially binds to DNA binding sites that are in an open chromatin configuration. .
Expression

Additional Images

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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14580-50
: 10 Items
Hurry! only 10 items left in stock.

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