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Antibody Product Overview
| ELK.No | ES14611 |
| Product name | MYH7B rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 57644 |
| Human Swiss-Prot | A7E2Y1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MYH7B |
| Fields | |
| Gene name | MYH7B KIAA1512 |
| Protein name | MYH7B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 668940 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | A2AQP0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human MYH7B AA range: 606-656 |
| Specificity | This antibody detects endogenous levels of MYH7B at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 214kD |
| Observed band (KD) | |
| Background | The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010], |
| Function | caution:This protein sequence has been named 'Slow A' MYH14 (PubMed:11919279), but it also appears also as 'Slow B' MYH15 within the reference.,developmental stage:Found in fetal liver and brain.,function:Involved in muscle contraction.,miscellaneous:Expression does not vary in normal patients compared to patients with acute monocytic leukemia.,miscellaneous:The cardiac alpha isoform is a 'fast' ATPase myosin, while the beta isoform is a 'slow' ATPase.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subunit:Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).,tissue specificity:Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expres |
| Subcellular location | Membrane ; Peripheral membrane protein . |
| Expression | Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen and liver. |
Additional Images
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Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14611-50
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