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Antibody Product Overview
| ELK.No | ES14679 |
| Product name | MTNB rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51074 |
| Human Swiss-Prot | Q96GX9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MTNB |
| Fields | >>Cysteine and methionine metabolism;>>Metabolic pathways |
| Gene name | APIP CGI-29 |
| Protein name | MTNB |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56369 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9WVQ5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human MTNB AA range: 133-183 |
| Specificity | This antibody detects endogenous levels of MTNB at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 27kD |
| Observed band (KD) | |
| Background | APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008], |
| Function | cofactor:Binds 1 zinc ion per subunit .,function:Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.,similarity:Belongs to the aldolase class II family. APIP subfamily.,subunit:Interacts with APAF1.,tissue specificity:Ubiquitously expressed with high expression in skeletal muscle, heart and kidney., |
| Subcellular location | Cytoplasm . |
| Expression | Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney. |
Additional Images
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14679-100
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