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Antibody Product Overview
| ELK.No | ES15020 |
| Product name | MBNL3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Muscleblind-like protein 3 (Cys3His CCG1-required protein) (Muscleblind-like X-linked protein) (Protein HCHCR) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 55796 |
| Human Swiss-Prot | Q9NUK0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MBNL3 |
| Fields | |
| Gene name | MBNL3 CHCR MBLX39 MBXL |
| Protein name | MBNL3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 171170 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R003 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human MBNL3 AA range: 184-234 |
| Specificity | This antibody detects endogenous levels of MBNL3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.58% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009], |
| Function | function:Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.,similarity:Belongs to the muscleblind family.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Greater concentration in the nucleus. In both myotonic dystrophy 1 (DM1) and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.,tissue specificity:Highly expressed in the placenta., |
| Subcellular location | Nucleus . Cytoplasm . Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts. |
| Expression | Highly expressed in the placenta. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15020-100
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