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Antibody Product Overview
| ELK.No | ES15025 |
| Product name | MAT2B rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 27430 |
| Human Swiss-Prot | Q9NZL9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MAT2B |
| Fields | >>Cysteine and methionine metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Biosynthesis of cofactors |
| Gene name | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 |
| Protein name | MAT2B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 108645 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q99LB6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 683630 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5U2R0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human MAT2B AA range: 23-73 |
| Specificity | This antibody detects endogenous levels of MAT2B at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 37kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012], |
| Function | function:Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.,miscellaneous:Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,similarity:Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,tissue specificity:Widely expressed., |
| Subcellular location | intracellular,nucleus,mitochondrion,cytosol,methionine adenosyltransferase complex,extracellular exosome, |
| Expression | Widely expressed. |
Additional Images
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15025-100
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