LRRN2 rabbit pAb

LRRN2 rabbit pAb

AO-06-ES15098-50

LRRN2 rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES15098
Product nameLRRN2 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA;IHC
Other name
Size50μL
Unit price ($)148
Human gene ID10446
Human Swiss-ProtO75325
SourceRabbit
IsotypeIgG
TargetLRRN2
Fields
Gene nameLRRN2 GAC1 LRRN5 UNQ256/PRO293
Protein nameLRRN2
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-Prot
Mouse Swiss link
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human LRRN2 AA range: 296-346
SpecificityThis antibody detects endogenous levels of LRRN2 at Human
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)78kD
Observed band (KD)
BackgroundThe protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
Functionsimilarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,tissue specificity:Overamplified in malignant gliomas.,
Subcellular locationMembrane ; Single-pass type I membrane protein .
ExpressionOveramplified in malignant gliomas.

Additional Images

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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
Image 2
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES15098-50
: 10 Items
Hurry! only 10 items left in stock.

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