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Antibody Product Overview
| ELK.No | ES15120 |
| Product name | LRC3B rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 116135 |
| Human Swiss-Prot | Q96PB8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LRC3B |
| Fields | |
| Gene name | LRRC3B LRP15 UNQ195/PRO221 |
| Protein name | LRC3B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 218763 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8VCH9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human LRC3B AA range: 115-165 |
| Specificity | This antibody detects endogenous levels of LRC3B at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 28kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015], |
| Function | similarity:Belongs to the LRRC3 family.,similarity:Contains 3 LRR (leucine-rich) repeats., |
| Subcellular location | Membrane ; Single-pass membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES15120-50
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