KR261 rabbit pAb

KR261 rabbit pAb

AO-06-ES15258-50

KR261 rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES15258
Product nameKR261 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB;IHC
Other name
Size50μL
Unit price ($)148
Human gene ID388818
Human Swiss-ProtQ6PEX3
SourceRabbit
IsotypeIgG
TargetKR261
Fields
Gene nameKRTAP26-1 KAP26.1
Protein nameKR261
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID69533
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9D7N2
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human KR261 AA range: 153-203
SpecificityThis antibody detects endogenous levels of KR261 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)23kD
Observed band (KD)
Background
Functionfunction:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Localized high up in the well differentiated portion of the hair follicle cuticle (about 10-15 cell layers above the apex of the dermal papilla).,
Subcellular locationintermediate filament,
ExpressionLocalized high up in the well differentiated portion of the hair follicle cuticle (about 10-15 cell layers above the apex of the dermal papilla).

Additional Images

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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
Image 2
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES15258-50
: 10 Items
Hurry! only 10 items left in stock.

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