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Antibody Product Overview
| ELK.No | ES15303 |
| Product name | KINH rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3799 |
| Human Swiss-Prot | P33176 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KINH |
| Fields | >>Endocytosis;>>Dopaminergic synapse;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Salmonella infection;>>Non-small cell lung cancer |
| Gene name | KIF5B KNS KNS1 |
| Protein name | KINH |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16573 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q61768 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 117550 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q2PQA9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human KINH AA range: 64-114 |
| Specificity | This antibody detects endogenous levels of KINH at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.266% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | |
| Function | domain:Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.,function:Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.,similarity:Belongs to the kinesin-like protein family.,similarity:Belongs to the kinesin-like protein family. Kinesin subfamily.,similarity:Contains 1 kinesin-motor domain.,subcellular location:Uniformly distributed between soma and neurites in hippocampal neurons.,subunit:Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity). Interacts with |
| Subcellular location | Cytoplasm, cytoskeleton . Cytolytic granule membrane . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Uniformly distributed between soma and neurites in hippocampal neurons. . |
| Expression | Muscle,Placenta,Uterus, |
Additional Images
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15303-50
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