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Antibody Product Overview
| ELK.No | ES15325 |
| Product name | KHK rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3795 |
| Human Swiss-Prot | P50053 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KHK |
| Fields | >>Fructose and mannose metabolism;>>Metabolic pathways |
| Gene name | KHK |
| Protein name | KHK |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 16548 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P97328 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25659 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q02974 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human KHK AA range: 102-152 |
| Specificity | This antibody detects endogenous levels of KHK at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 33kD |
| Observed band (KD) | |
| Background | This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:ATP + D-fructose = ADP + D-fructose 1-phosphate.,caution:Form C has not yet been fully sequenced in its N-terminal (from 1-69).,disease:Defects in KHK are the cause of fructosuria [MIM:229800]. Fructosuria is a benign defect of intermediary metabolism.,enzyme regulation:Requires potassium. Inhibition by ADP.,pathway:Carbohydrate metabolism; fructose metabolism.,similarity:Belongs to the carbohydrate kinase pfkB family.,subunit:Dimer of A-A, A-C or C-C.,tissue specificity:Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye., |
| Subcellular location | cytoplasm,cytosol,extracellular exosome, |
| Expression | Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15325-50
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