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Antibody Product Overview
| ELK.No | ES15413 |
| Product name | ITF Polyclonal Rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | IHC; ELISA |
| Other name | Trefoil factor 3 (Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 7033 |
| Human Swiss-Prot | Q07654 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ITF |
| Fields | |
| Gene name | TFF3 ITF TFI |
| Protein name | ITF Polyclonal |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ITF Polyclonal AA range: 1-50 |
| Specificity | This antibody detects endogenous levels of human ITF Polyclonal |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | |
| Background | Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008], |
| Function | function:Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).,similarity:Contains 1 P-type (trefoil) domain.,subunit:Monomer. Homodimer; disulfide-linked.,tissue specificity:Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . Cytoplasm . |
| Expression | Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level). |
Additional Images
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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: AO-06-ES15413-50
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