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Antibody Product Overview
| ELK.No | ES15491 |
| Product name | IKZF5 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 64376 |
| Human Swiss-Prot | Q9H5V7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IKZF5 |
| Fields | |
| Gene name | IKZF5 ZNFN1A5 |
| Protein name | IKZF5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67143 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BU00 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human IKZF5 AA range: 210-260 |
| Specificity | This antibody detects endogenous levels of IKZF5 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 46kD |
| Observed band (KD) | |
| Background | Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Pegasus, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002], |
| Function | domain:C-terminal zinc fingers mediate homodimerization.,domain:The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.,function:DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.,miscellaneous:'Pegasus' was the winged horse in Greek mythology.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Self-associates and interacts with other family members; IKZF1, IKZF2, IKZF3 AND IKZF4.,tissue specificity:Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively., |
| Subcellular location | Nucleus . |
| Expression | Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES15491-50
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