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Antibody Product Overview
| ELK.No | ES1565 |
| Product name | ABCC12 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 94160 |
| Human Swiss-Prot | Q96J65 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ABCC12 |
| Fields | >>ABC transporters |
| Gene name | ABCC12 |
| Protein name | Multidrug resistance-associated protein 9 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q80WJ6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRP9. AA range:691-740 |
| Specificity | ABCC12 Polyclonal Antibody detects endogenous levels of ABCC12 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 170kD |
| Background | This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Expressed in fetal tissues.,function:Probable transporter.,similarity:Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily.,similarity:Contains 2 ABC transmembrane type-1 domains.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Expressed in testis (at protein level). Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression | Expressed in testis (at protein level). Widely expressed at low level (PubMed:11483364, PubMed:11688999, PubMed:12011458, PubMed:17472575). Isoform 5 is specifically expressed in brain, testis and breast cancer cells (PubMed:11483364, PubMed:11688999, PubMed:12011458). |
Additional Images
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Western Blot analysis of various cells using ABCC12 Polyclonal Antibody diluted at 1:500
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Western blot analysis of lysates from 293, HepG2, and HUVEC cells, using MRP9 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES1565-50
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