| ELK.No | ES15905 |
| Product name | GRIK4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Glutamate receptor, ionotropic kainate 4 (Excitatory amino acid receptor 1) (EAA1) (Glutamate receptor KA-1) (KA1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2900 |
| Human Swiss-Prot | Q16099 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GRIK4 |
| Fields | >>Neuroactive ligand-receptor interaction;>>Glutamatergic synapse |
| Gene name | GRIK4 GRIK |
| Protein name | GRIK4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 110637 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BMF5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24406 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q01812 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human GRIK4 AA range: 466-516 |
| Specificity | This antibody detects endogenous levels of GRIK4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.239% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013], |
| Function | function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Forms a heteromeric channel with GRIK1 or GRIK3., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Expression | Hippocampus,Kidney, |

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