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Antibody Product Overview
| ELK.No | ES1614 |
| Product name | AIFL rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IHC;IF;ELISA |
| Other name | AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 150209 |
| Human Swiss-Prot | Q96NN9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AIFL |
| Fields | |
| Gene name | AIFM3 |
| Protein name | Apoptosis-inducing factor 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72168 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3TY86 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59 |
| Specificity | AIFL Polyclonal Antibody detects endogenous levels of AIFL protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 67kD |
| Background | domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level)., |
| Function | domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level)., |
| Subcellular location | Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis. |
| Expression | Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). |
Additional Images
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Western Blot analysis of various cells using AIFL Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using AIFM3 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain, using AIFM3 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES1614-50
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