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Antibody Product Overview
| ELK.No | ES16171 |
| Product name | GLTL5 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 168391 |
| Human Swiss-Prot | Q7Z4T8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GLTL5 |
| Fields | >>Mucin type O-glycan biosynthesis;>>Other types of O-glycan biosynthesis;>>Metabolic pathways |
| Gene name | GALNTL5 GALNT15 |
| Protein name | GLTL5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67909 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D4M9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human GLTL5 AA range: 79-129 |
| Specificity | This antibody detects endogenous levels of GLTL5 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 49kD |
| Observed band (KD) | |
| Background | |
| Function | caution:In contrast to other members of the family, it lacks the C-terminal ricin B-type lectin domain, which contributes to the glycopeptide specificity. Its precise function is therefore unsure.,cofactor:Calcium.,cofactor:Manganese.,domain:There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.,function:May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.,online information:GlycoGene database,online information:Putative polypeptide N-acetylgalactosaminyltransferase-like protein |
| Subcellular location | Late endosome membrane ; Single-pass type II membrane protein . Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity). . |
| Expression | Mainly expressed in testis. Weakly or not expressed in other tissues. |
Additional Images
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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16171-50
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