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Antibody Product Overview
| ELK.No | ES16187 |
| Product name | GGT6 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 124975 |
| Human Swiss-Prot | Q6P531 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GGT6 |
| Fields | >>Taurine and hypotaurine metabolism;>>Glutathione metabolism;>>Metabolic pathways |
| Gene name | GGT6 |
| Protein name | GGT6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 71522 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6PDE7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 408206 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6IE08 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human GGT6 AA range: 254-304 |
| Specificity | This antibody detects endogenous levels of GGT6 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 54kD |
| Observed band (KD) | |
| Background | GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008], |
| Function | catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,function:Cleaves glutathione conjugates.,pathway:Sulfur metabolism; glutathione metabolism.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain., |
| Subcellular location | Membrane ; Single-pass type II membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16187-50
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