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Antibody Product Overview
| ELK.No | ES16226 |
| Product name | GBRAP rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 11337 |
| Human Swiss-Prot | O95166 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GBRAP |
| Fields | >>FoxO signaling pathway;>>Autophagy - other;>>Mitophagy - animal;>>Autophagy - animal;>>NOD-like receptor signaling pathway;>>GABAergic synapse |
| Gene name | GABARAP FLC3B HT004 |
| Protein name | GBRAP |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56486 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9DCD6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 58974 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P60517 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human GBRAP AA range: 8-58 |
| Specificity | This antibody detects endogenous levels of GBRAP at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 13kD |
| Observed band (KD) | |
| Background | Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008], |
| Function | function:May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.,subunit:Interacts with GPHN and NSF (By similarity). Interacts with GABRG2, beta-tubulin and ULK1.,tissue specificity:Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas., |
| Subcellular location | Cytoplasmic vesicle, autophagosome membrane . Endomembrane system . Cytoplasm, cytoskeleton . Golgi apparatus membrane . Cytoplasmic vesicle . Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity). . |
| Expression | Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16226-50
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