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Antibody Product Overview
| ELK.No | ES16344 |
| Product name | FOXG1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2290 |
| Human Swiss-Prot | P55316 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FOXG1 |
| Fields | >>FoxO signaling pathway |
| Gene name | FOXG1 FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FOXG1A FOXG1B FOXG1C |
| Protein name | FOXG1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 15228 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q60987 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 24370 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q00939 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FOXG1 AA range: 247-297 |
| Specificity | This antibody detects endogenous levels of FOXG1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 54kD |
| Observed band (KD) | |
| Background | This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012], |
| Function | caution:PubMed:7959731 claims that there are 3 different FOXG1 proteins, FOXG1A, FOXG1B, and FOXG1C. It was latter found that there is only one gene and the differences between these three may be sequencing errors since the protein is coded in a unique exon.,function:Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Interacts with KDM5B.,tissue specificity:Expression is restricted to the neurons of the developing telencephalon., |
| Subcellular location | Nucleus . |
| Expression | Expression is restricted to the neurons of the developing telencephalon. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16344-100
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