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Antibody Product Overview
| ELK.No | ES16356 |
| Product name | FMT rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 123263 |
| Human Swiss-Prot | Q96DP5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FMT |
| Fields | >>One carbon pool by folate;>>Aminoacyl-tRNA biosynthesis;>>Metabolic pathways |
| Gene name | MTFMT FMT FMT1 |
| Protein name | FMT |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 69606 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D799 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 315763 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5I0C5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FMT AA range: 115-165 |
| Specificity | This antibody detects endogenous levels of FMT at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 43kD |
| Observed band (KD) | |
| Background | The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011], |
| Function | catalytic activity:10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).,domain:Composed of an N- and a C-terminal domain. The N-terminal domain carries the tetrahydrofolate (THF)-binding site and the C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction.,function:Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.,similarity:Belongs to the fmt family., |
| Subcellular location | Mitochondrion . |
| Expression |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16356-50
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