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Antibody Product Overview
| ELK.No | ES16499 |
| Product name | FBXL5 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 26234 |
| Human Swiss-Prot | Q9UKA1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FBXL5 |
| Fields | |
| Gene name | FBXL5 FBL4 FBL5 FLR1 |
| Protein name | FBXL5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 242960 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8C2S5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human FBXL5 AA range: 319-369 |
| Specificity | This antibody detects endogenous levels of FBXL5 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 76kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010], |
| Function | function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,similarity:Contains 1 F-box domain.,similarity:Contains 4 LRR (leucine-rich) repeats.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex., |
| Subcellular location | Cytoplasm, perinuclear region . |
| Expression |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16499-50
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