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Antibody Product Overview
| ELK.No | ES16500 |
| Product name | FBXL4 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 26235 |
| Human Swiss-Prot | Q9UKA2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FBXL4 |
| Fields | |
| Gene name | FBXL4 FBL4 FBL5 |
| Protein name | FBXL4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 269514 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BH70 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human FBXL4 AA range: 396-446 |
| Specificity | This antibody detects endogenous levels of FBXL4 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 68kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | similarity:Contains 1 F-box domain.,similarity:Contains 8 LRR (leucine-rich) repeats.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,tissue specificity:Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle., |
| Subcellular location | Cytoplasm. Nucleus. Mitochondrion. |
| Expression | Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle. |
Additional Images
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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16500-50
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