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Antibody Product Overview
| ELK.No | ES16501 |
| Product name | FBX6 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26270 |
| Human Swiss-Prot | Q9NRD1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FBX6 |
| Fields | >>Protein processing in endoplasmic reticulum |
| Gene name | FBXO6 FBG2 FBS2 FBX6 |
| Protein name | FBX6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 50762 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QZN4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 192351 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q923V4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FBX6 AA range: 30-80 |
| Specificity | This antibody detects endogenous levels of FBX6 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 32kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008], |
| Function | function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,online information:hFBG2,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex., |
| Subcellular location | Cytoplasm . |
| Expression |
Additional Images
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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16501-100
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