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Antibody Product Overview
| ELK.No | ES16507 |
| Product name | FBX17 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 115290 |
| Human Swiss-Prot | Q96EF6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FBX17 |
| Fields | |
| Gene name | FBXO17 FBG4 FBX17 FBX26 FBXO26 |
| Protein name | FBX17 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 50760 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QZM8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 292757 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6AY27 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FBX17 AA range: 61-111 |
| Specificity | This antibody detects endogenous levels of FBX17 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 31kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Directly interacts with SKP1A and CUL1.,tissue specificity:Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain., |
| Subcellular location | SCF ubiquitin ligase complex, |
| Expression | Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain. |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16507-50
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