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Antibody Product Overview
| ELK.No | ES16529 |
| Product name | FAM5C rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Protein FAM5C (DBCCR1-like protein 1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 339479 |
| Human Swiss-Prot | Q76B58 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FAM5C |
| Fields | |
| Gene name | FAM5C DBCCR1L DBCCR1L1 |
| Protein name | FAM5C |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 215378 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q499E0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 286901 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8K1M7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human FAM5C AA range: 503-553 |
| Specificity | This antibody detects endogenous levels of FAM5C at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.314% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015], |
| Function | similarity:Belongs to the FAM5 family., |
| Subcellular location | Secreted . Mitochondrion . |
| Expression | Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16529-50
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