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Antibody Product Overview
| ELK.No | ES16638 |
| Product name | F111A rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 63901 |
| Human Swiss-Prot | Q96PZ2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | F111A |
| Fields | |
| Gene name | FAM111A KIAA1895 |
| Protein name | F111A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 107373 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D2L9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human F111A AA range: 264-314 |
| Specificity | This antibody detects endogenous levels of F111A at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 67kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015], |
| Function | similarity:Belongs to the FAM111 family., |
| Subcellular location | Nucleus . Chromosome . Cytoplasm . Mainly localizes to nucleus: colocalizes with PCNA on replication sites. . |
| Expression |
Additional Images
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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16638-100
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