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Antibody Product Overview
| ELK.No | ES16668 |
| Product name | EST4A rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Carboxylesterase 4A (EC 3.1.1.-) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 283848 |
| Human Swiss-Prot | Q5XG92 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EST4A |
| Fields | |
| Gene name | CES4A CES8 UNQ440/PRO873 |
| Protein name | EST4A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8R0W5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human EST4A AA range: 441-491 |
| Specificity | This antibody detects endogenous levels of EST4A at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.87% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2010], |
| Function | function:Probable carboxylesterase.,similarity:Belongs to the type-B carboxylesterase/lipase family., |
| Subcellular location | Secreted . |
| Expression | Blood,Brain,Uterus, |
Additional Images
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Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16668-50
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