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Antibody Product Overview
| ELK.No | ES16696 |
| Product name | ERC2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | ERC protein 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26059 |
| Human Swiss-Prot | O15083 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ERC2 |
| Fields | |
| Gene name | ERC2 KIAA0378 |
| Protein name | ERC2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 238988 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6PH08 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 259269 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8K3M6 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ERC2 AA range: 368-418 |
| Specificity | This antibody detects endogenous levels of ERC2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.246% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015], |
| Function | function:Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.,sequence caution:Contaminating sequence. Sequence of unknown origin in the N-terminal part.,subcellular location:In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density.,subunit:Interacts with BSN, ERC1, PPFIA1, PPFIA2, PPFIA3 and PPFIA4. Interacts through its C-terminus with the PDZ domain of RIMS1. Part of a complex consisting of ERC2, RIMS1 and UNC13A., |
| Subcellular location | Cytoplasm . Cell junction, synapse . Cell junction, synapse, presynaptic active zone . Cytoplasm, cytoskeleton . In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density (By similarity). . |
| Expression | Brain,Epithelium,PNS, |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16696-100
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