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Antibody Product Overview
| ELK.No | ES16740 |
| Product name | EP400 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | IHC;IF |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 57634 |
| Human Swiss-Prot | Q96L91 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EP400 |
| Fields | |
| Gene name | EP400 CAGH32 KIAA1498 KIAA1818 TNRC12 |
| Protein name | EP400 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 75560 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CHI8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human EP400 AA range: 2057-2107 |
| Specificity | This antibody detects endogenous levels of EP400 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | IHC-p 1：50-200 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 347kD |
| Observed band (KD) | |
| Background | |
| Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similar |
| Subcellular location | Nucleus . |
| Expression | Ubiquitously expressed. |
Additional Images
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Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES16740-100
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