ELF2 rabbit pAb

ELF2 rabbit pAb

AO-06-ES16764-100

ELF2 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES16764
Product nameELF2 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other name
Size100μL
Unit price ($)248
Human gene ID1998
Human Swiss-ProtQ15723
SourceRabbit
IsotypeIgG
TargetELF2
Fields
Gene nameELF2 NERF
Protein nameELF2
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID69257
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9JHC9
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human ELF2 AA range: 80-130
SpecificityThis antibody detects endogenous levels of ELF2 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)65kD
Observed band (KD)
Background
Functionfunction:Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. Isoform 2 may function in repression of RUNX1-mediated transactivation.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Interacts with the LIM domains of LMO2 (By similarity). Interacts via its N-terminal region with RUNX1.,tissue specificity:Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.,
Subcellular locationNucleus.
ExpressionExpressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.

Additional Images

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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16764-100
: 10 Items
Hurry! only 10 items left in stock.

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