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Antibody Product Overview
| ELK.No | ES16775 |
| Product name | EI24 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9538 |
| Human Swiss-Prot | O14681 |
| Source | Rabbit |
| Isotype | IgG |
| Target | EI24 |
| Fields | >>p53 signaling pathway |
| Gene name | EI24 PIG8 |
| Protein name | EI24 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13663 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q61070 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 300514 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4KM77 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human EI24 AA range: 107-157 |
| Specificity | This antibody detects endogenous levels of EI24 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 37kD |
| Observed band (KD) | |
| Background | This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014], |
| Function | induction:By TP53/p53.,similarity:Belongs to the EI24 family., |
| Subcellular location | Nucleus membrane ; Multi-pass membrane protein . Cytoplasm . Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16775-50
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