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Antibody Product Overview
| ELK.No | ES16879 |
| Product name | DUS15 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 128853 |
| Human Swiss-Prot | Q9H1R2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DUS15 |
| Fields | |
| Gene name | DUSP15 C20orf57 VHY |
| Protein name | DUS15 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 252864 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R4V2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human DUS15 AA range: 15-65 |
| Specificity | This antibody detects endogenous levels of DUS15 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 32kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], |
| Function | catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,caution:Although assigned as two separate genes (c20orf57 and DUSP15), it is probable that C20orf57 does not exist by itself and is a part of the DUSP15 gene.,PTM:Isoform 3 is N-myristoylated.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Highly expressed in testis., |
| Subcellular location | Cytoplasm .; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side. |
| Expression | Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334). |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16879-50
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