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Antibody Product Overview
| ELK.No | ES16908 |
| Product name | DPM3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | IHC;IF |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 54344 |
| Human Swiss-Prot | Q9P2X0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DPM3 |
| Fields | >>N-Glycan biosynthesis;>>Metabolic pathways |
| Gene name | DPM3 |
| Protein name | DPM3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 68563 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D1Q4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human DPM3 AA range: 14-64 |
| Specificity | This antibody detects endogenous levels of DPM3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | IHC-p 1：50-200 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 10kD |
| Observed band (KD) | |
| Background | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008], |
| Function | function:Stabilizer subunit of the dolichol-phosphate-mannose synthase complex.,online information:GlycoGene database,similarity:Belongs to the DPM3 family.,subunit:Composed of three subunits; DPM1, DPM2 and DPM3. Associated with DPM1 via its C-terminal domain and with DPM2 via its N-terminal portion., |
| Subcellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Expression |
Additional Images
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES16908-100
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