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Antibody Product Overview
| ELK.No | ES16954 |
| Product name | DGAT1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8694 |
| Human Swiss-Prot | O75907 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DGAT1 |
| Fields | >>Glycerolipid metabolism;>>Retinol metabolism;>>Metabolic pathways;>>Fat digestion and absorption |
| Gene name | DGAT1 AGRP1 DGAT |
| Protein name | DGAT1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13350 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z2A7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 84497 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9ERM3 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human DGAT1 AA range: 405-455 |
| Specificity | This antibody detects endogenous levels of DGAT1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 54kD |
| Observed band (KD) | |
| Background | This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013], |
| Function | catalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,function:Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.,pathway:Lipid metabolism; glycerolipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16954-100
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