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Antibody Product Overview
| ELK.No | ES16987 |
| Product name | DDAH1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 23576 |
| Human Swiss-Prot | O94760 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DDAH1 |
| Fields | |
| Gene name | DDAH1 DDAH |
| Protein name | DDAH1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 69219 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CWS0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 64157 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O08557 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human DDAH1 AA range: 115-165 |
| Specificity | This antibody detects endogenous levels of DDAH1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 31kD |
| Observed band (KD) | |
| Background | This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.,cofactor:Binds 1 zinc ion.,function:Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation.,similarity:Belongs to the DDAH family.,subunit:Monomer., |
| Subcellular location | mitochondrion,cytosol,extracellular exosome, |
| Expression | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16987-50
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