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Antibody Product Overview
| ELK.No | ES16991 |
| Product name | DCNL3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 123879 |
| Human Swiss-Prot | Q8IWE4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DCNL3 |
| Fields | |
| Gene name | DCUN1D3 |
| Protein name | DCNL3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 233805 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K0V2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 309035 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4V8B2 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human DCNL3 AA range: 205-255 |
| Specificity | This antibody detects endogenous levels of DCNL3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 33kD |
| Observed band (KD) | |
| Background | |
| Function | similarity:Contains 1 DCUN1 domain., |
| Subcellular location | Cell membrane . Cytoplasm . Nucleus . Cytoplasm, perinuclear region . After UVC treatment, the protein enters to the nucleus gradually (PubMed:18823379). Cell membrane localization is essential for CUL3 neddylation (PubMed:19617556). . |
| Expression | Tends to be down-regulated in different type of cancers, including lung neuroendocrine carcinoma, thyroid Huerthle cell carcinoma and lung squamous cell carcinoma (PubMed:25349211). Mostly expressed in testis and brain (PubMed:26906416). Highly expressed in liver, bladder and renal normal tissue than their tumor tissue counterparts (PubMed:18823379). Palmitoylation stabilizes DCUN1D3 at the cell membrane (PubMed:19617556). |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES16991-100
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