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Antibody Product Overview
| ELK.No | ES17132 |
| Product name | CYH4 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 27128 |
| Human Swiss-Prot | Q9UIA0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CYH4 |
| Fields | >>Phospholipase D signaling pathway;>>Endocytosis;>>Pathogenic Escherichia coli infection;>>Shigellosis;>>Salmonella infection |
| Gene name | CYTH4 CYT4 PSCD4 |
| Protein name | CYH4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72318 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80YW0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CYH4 AA range: 150-200 |
| Specificity | This antibody detects endogenous levels of CYH4 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 43kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015], |
| Function | function:Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,tissue specificity:Expressed predominantly in peripheral blood leukocytes., |
| Subcellular location | Cell membrane ; Peripheral membrane protein . |
| Expression | Expressed predominantly in peripheral blood leukocytes. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17132-100
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