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Antibody Product Overview
| ELK.No | ES17348 |
| Product name | CNNM4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26504 |
| Human Swiss-Prot | Q6P4Q7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CNNM4 |
| Fields | |
| Gene name | CNNM4 ACDP4 KIAA1592 |
| Protein name | CNNM4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 94220 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q69ZF7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 363216 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P0C588 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CNNM4 AA range: 18-68 |
| Specificity | This antibody detects endogenous levels of CNNM4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.358% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010], |
| Function | function:Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions.,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,subunit:Interacts with COX11.,tissue specificity:Widely expressed. Highly expressed in heart., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Widely expressed. Highly expressed in heart. |
Additional Images
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Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17348-100
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