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Antibody Product Overview
| ELK.No | ES17382 |
| Product name | CLCB rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 1212 |
| Human Swiss-Prot | P09497 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CLCB |
| Fields | >>Lysosome;>>Endocytosis;>>Synaptic vesicle cycle;>>Endocrine and other factor-regulated calcium reabsorption;>>Huntington disease;>>Bacterial invasion of epithelial cells |
| Gene name | CLTB |
| Protein name | CLCB |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74325 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6IRU5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 116561 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P08082 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human CLCB AA range: 168-218 |
| Specificity | This antibody detects endogenous levels of CLCB at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 25kD |
| Observed band (KD) | |
| Background | Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008], |
| Function | function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.,subcellular location:Cytoplasmic face of coated pits and vesicles.,subunit:Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R., |
| Subcellular location | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles. |
| Expression |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17382-100
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