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Antibody Product Overview
| ELK.No | ES1740 |
| Product name | BACH1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | BACH1; Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 571 |
| Human Swiss-Prot | O14867 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BACH1 |
| Fields | |
| Gene name | BACH1 |
| Protein name | Transcription regulator protein BACH1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P97302 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BACH1. AA range:131-180 |
| Specificity | BACH1 Polyclonal Antibody detects endogenous levels of BACH1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 100kD |
| Background | This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009], |
| Function | function:Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain., |
| Subcellular location | Nucleus . |
| Expression | Epithelium,Placenta,Trachea, |
Additional Images
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Western Blot analysis of various cells using BACH1 Polyclonal Antibody
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Immunofluorescence analysis of HeLa cells, using BACH1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HepG2 cells, using BACH1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using BACH1 antibody.
: AO-06-ES1740-50
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