Français
English
Antibody Product Overview
| ELK.No | ES17409 |
| Product name | CL12B rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 387837 |
| Human Swiss-Prot | Q2HXU8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CL12B |
| Fields | |
| Gene name | CLEC12B UNQ5782/PRO16089 |
| Protein name | CL12B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 71183 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q149M0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CL12B AA range: 111-161 |
| Specificity | This antibody detects endogenous levels of CL12B at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 30kD |
| Observed band (KD) | |
| Background | |
| Function | domain:Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.,function:Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.,induction:Down-regulated in activated leukocytes recruited to a site of inflammation.,PTM:Highly N-glycosylated. Glycosylation varies between cell types.,similarity:Contains 1 C-type lectin domain.,subcellular location:Ligand binding leads to internalization.,subunit:Homodimer. Interacts with PTPN6 a |
| Subcellular location | Cell membrane ; Single-pass type II membrane protein . |
| Expression | Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis (PubMed:17562706). Expressed in melanocytes (at protein level) (PubMed:34310951). |
Additional Images
No image
Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES17409-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package