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Antibody Product Overview
| ELK.No | ES17472 |
| Product name | CHP3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 54997 |
| Human Swiss-Prot | Q96BS2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CHP3 |
| Fields | |
| Gene name | TESC CHP3 |
| Protein name | CHP3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 57816 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JKL5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CHP3 AA range: 20-70 |
| Specificity | This antibody detects endogenous levels of CHP3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 24kD |
| Observed band (KD) | |
| Background | |
| Function | caution:It is uncertain whether Met-1 or Met-54 is the initiator.,cofactor:Binds calcium.,developmental stage:Strongly up-regulated in K562 cells treated by PMA to promote megakaryocytic differentiation, but not when treated by DMSO to promote granulocytic differentiation or by hemin to promote erythroid differentiation (at protein level).,function:Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.,similarity:Contains 1 EF-hand domain.,subunit:Interacts with Sodium/hydrogen exchanger 1 (SLC9A1).,tissue specificity:Abundantly expressed in heart., |
| Subcellular location | Nucleus . Cytoplasm . Membrane ; Lipid-anchor . Cell membrane . Cell projection, lamellipodium . Cell projection, ruffle membrane . Colocalizes with SLC9A1 at the plasma membrane. . |
| Expression | Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17472-50
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