CEP85 rabbit pAb

CEP85 rabbit pAb

AO-06-ES17522-50

CEP85 rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES17522
Product nameCEP85 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other nameCentrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21)
Size50μL
Unit price ($)148
Human gene ID64793
Human Swiss-ProtQ6P2H3
SourceRabbit
IsotypeIgG
TargetCEP85
Fields
Gene nameCEP85 CCDC21
Protein nameCEP85
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID70012
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ8BMK0
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human CEP85 AA range: 267-317
SpecificityThis antibody detects endogenous levels of CEP85 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.295% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)85kD
BackgroundThis gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Functionsimilarity:Belongs to the CCDC21 family.,
Subcellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856). .
ExpressionHepatoma,Placenta,Retinoblastoma,Testis,

Additional Images

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Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17522-50
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