| ELK.No | ES17522 |
| Product name | CEP85 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Centrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 64793 |
| Human Swiss-Prot | Q6P2H3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CEP85 |
| Fields | |
| Gene name | CEP85 CCDC21 |
| Protein name | CEP85 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 70012 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BMK0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CEP85 AA range: 267-317 |
| Specificity | This antibody detects endogenous levels of CEP85 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.295% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | similarity:Belongs to the CCDC21 family., |
| Subcellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856). . |
| Expression | Hepatoma,Placenta,Retinoblastoma,Testis, |

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