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Antibody Product Overview
| ELK.No | ES18057 |
| Product name | BHE40 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8553 |
| Human Swiss-Prot | O14503 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BHE40 |
| Fields | >>Circadian rhythm |
| Gene name | BHLHE40 BHLHB2 DEC1 SHARP2 STRA13 |
| Protein name | BHE40 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20893 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O35185 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 79431 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | O35780 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human BHE40 AA range: 229-279 |
| Specificity | This antibody detects endogenous levels of BHE40 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 45kD |
| Observed band (KD) | |
| Background | This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014], |
| Function | function:May function as a transcriptional factor to modulate chondrogenesis in response to the cAMP pathway.,PTM:Ubiquitinated; which may lead to proteasomal degradation.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 Orange domain.,subunit:Able to homodimerize or heterodimerize with TCF3/E47. Interacts with ubiquitin-conjugating enzyme UBE2I/UBC9.,tissue specificity:Expressed in cartilage, spleen, intestine, lung, and to a lesser extent in heart, brain, liver, muscle and stomach., |
| Subcellular location | Cytoplasm . Nucleus . Predominantly localized in the nucleus (PubMed:11278694). . |
| Expression | Expressed in cartilage, spleen, intestine, lung, and to a lesser extent in heart, brain, liver, muscle and stomach. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18057-100
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